Where is carbonic anhydrase made




















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Access through your institution. Buy or subscribe. Rent or Buy article Get time limited or full article access on ReadCube. References 1 Meldrum, N. From there, the CO2 is all ready to be exhaled from the lungs and is released through the mouth. In conclusion, the enzyme carbonic anhydrase is used to balance the blood pH levels, and also to allow humans to breathe out carbon dioxide, more commonly known as CO2.

It catalyzes the reaction to convert CO2 to carbonic acid, which breaks down into bicarbonate ions and protons. Coli Recombinant. Shipped with Ice Packs Add to Cart. Back to Top. Carbonic Anhydrase II E. About Carbonic Anhydrase: The role of carbonic anhydrase -- which is found in red blood cells -- is to catalyze a reaction that converts CO2 and water into carbonic acid.

Educational portal of. Molecule of the Month. Carbonic Anhydrase Carbonic anhydrase solubilizes carbon dioxide gas so we can breathe it out Alpha top , beta middle , and gamma bottom carbonic anhydrases. Breathing is a fundamental function in life - ever wondered what really happens when we breathe? The air we breathe in has precious oxygen that fuels the breakdown of sugars and fat in our cells.

In our lungs, oxygen diffuses into the blood, binds to hemoglobin and is transported to all the cells of our body see the Molecule of the Month feature on hemoglobin. Carbon dioxide is a byproduct of sugar and fat breakdown in cells and needs to be removed from our body. Again, blood acts as a transport medium. An enzyme present in red blood cells, carbonic anhydrase, aids in the conversion of carbon dioxide to carbonic acid and bicarbonate ions.

When red blood cells reach the lungs, the same enzyme helps to convert the bicarbonate ions back to carbon dioxide, which we breathe out. Although these reactions can occur even without the enzyme, carbonic anhydrase can increase the rate of these conversions up to a million fold.

Plants also use oxygen for producing energy, and also release carbon dioxide. Green plants can convert water and carbon dioxide into sugars in the presence of sunlight. This process, photosynthesis, uses carbon dioxide from the atmosphere. Gaseous carbon dioxide is stored in plants as bicarbonate ions. In both land and water plants, carbonic anhydrase plays a role in converting bicarbonate ions back to carbon dioxide for photosynthesis.

Another interesting biological phenomenon where this enzyme plays a role is the calcification of corals. Seawater calcium reacts with the bicarbonate produced by carbonic anhydrase from the coral polyps, forming calcium carbonate. This is deposited as the hard exterior of corals.

Carbonic anhydrase is an enzyme that assists rapid inter-conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. This enzyme was first identified in , in red blood cells of cows. Since then, it has been found to be abundant in all mammalian tissues, plants, algae and bacteria. This ancient enzyme has three distinct classes called alpha, beta and gamma carbonic anhydrase. Members of these different classes share very little sequence or structural similarity, yet they all perform the same function and require a zinc ion at the active site.



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